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Depression after accutane
So your dermatologist recommended you start taking isotretinoin (AKA. Accutane ) for your acne. . But you're nervous depression after accutane because you've heard that isotretinoin medications can cause depression and suicidal thoughts. It's understandable to be a bit unnerved by the idea, and it's smart to do your research. Only you can decide if the benefits of taking isotretinoin outweigh the potential side effects. First, let's learn a bit about this medication. Isotretinoin is an oral medication that is used to treat severe acne. It is sometimes used to treat acne that isn't necessarily severe, but stubborn and not clearing up with other acne medications. Isotretinoin is sold under many different names, like Absorica and Zenatane, and also as generic isotretinoin. All of these medications have the same active ingredient and all work in the same way. All isotretinoin medications are prescription only, and you must register in the iPledge program before you may fill your prescription. Does Isotretinoin Cause Depression? There is no absolute proven link between isotretinoin and depression. For every study that has found a higher risk of depression in isotretinoin users, there is another that found no such risk. But for a small number of people, it seems isotretinoin may trigger depression. All in all, depression in people taking isotretinoin is fairly uncommon. . Depending on which study you look at, depression happens in anywhere from depression after accutane 1 to 11 of people taking the medication. This doesn't necessarily mean the isotretinoin was causing the depression, though. Depression can happen to anyone, whether taking isotretinoin or not. Those With a History of Depression Seem to Be More Susceptible. Some people seem to be more susceptible to isotretinoin-induced depression than most. While depression occurred in some people with no prior history of the disorder, many people had other risk factors, such as substance abuse, a family history of depression, or stressful events in their lives, which may have contributed to their depression. For people with bipolar disorder, there also seems to be an exacerbation of depression while taking isotretinoin. It's important depression after accutane to remember, though, that just because you're taking isotretinoin does not mean you will become depressed. Most people who did become depressed while using isotretinoin found that their symptoms went away once they stopped using the drug. . But for some people, depression and suicidal behavior persisted in some cases, even after they quit using isotretinoin. There Is No Proven Link, but There are a Few Theories. While case reports suggest a relationship between isotretinoin use and depression, there is no proven link. Still, some research has presented a few theories. Isotretinoin is derived from vitamin. . Vitamin A is responsible for many functions in the central nervous system. Researchers believe isotretinoin may disrupt the way serotonin is made and utilized by the body. Low levels of serotonin have been linked to depression, bipolar disorder, anxiety disorders, and aggression. Another theory looks at how isotretinoin causes changes in the area of the brain called the hippocampus. The hippocampus creates neurons constantly, a process called neurogenesis.