Prednisone is a corticosteroid, a man-made form of the steroids that the body naturally produces to fight illnesses and injuries. Prednisone acts as a replacement for people with low levels of cortisol, one of the natural steroid hormones. The drug also can effects of long term prednisone use also effectively reduce swelling and redness. Doctors prescribe prednisone alone or in combination with other medications to treat a variety of conditions, including: Certain forms of arthritis, effects of long term prednisone use some forms of cancer, severe allergic reactions. Multiple sclerosis, lupus, lung diseases, skin conditions, eye problems. Kidney disease, thyroid disease, stomach and intestinal problems, some people with. HIV effects of long term prednisone use who develop a certain type of pneumonia may also take prednisone along with antibiotics. The Schering Corporation (now Schering Plough) first introduced prednisone in 1955 under the brand name Meticorten. Today, a number of drug companies produce the drug, which is available in generic form. Currently available brand names include Sterapred, Sterapred DS, and Prednisone Intensol. Older brand names that are no longer on the market include Cortan, Deltasone, and Orasone. A 2012 study found that giving people with early-stage rheumatoid arthritis low doses of prednisone, plus the RA drug methotrexate, increased the effectiveness of methotrexate. Prednisone Warnings, prednisone can make it harder for your immune system to fight infection. If you do get an infection, you may not develop typical symptoms. Because of this, while you are taking prednisone, be sure to avoid people who are sick as well as those who have chickenpox or measles. It's also a good idea to wash your hands often and take other common-sense precautions. Children who take prednisone may grow effects of long term prednisone use and develop more slowly, so their pediatrician must monitor them closely while they're taking this medication. Be sure to talk to your child's doctor about this risk. Prednisone may increase your risk for osteoporosis, a disease that weakens bones so much that they become fragile and break easily. Let your doctor know if you have osteoporosis or are at increased risk for the condition. There are steps you can take to protect your bone health. Research also has shown that some people taking prednisone or similar medications have developed a type of cancer called Kaposi's sarcoma. People with this form of cancer develop patches of abnormal tissue under the skin, in the lining of the mouth, nose, and throat, or in other organs. Be sure to let you doctor know if you have an eye infection or have recurring eye infections. Also tell your doctor if you've ever had threadworms, a type of worm that can live inside the body. Your doctor also needs to know if you have any of the following: If you plan to take prednisone, don't get any vaccinations without talking to your doctor first. Pregnancy and Prednisone Prednisone is considered risky for expectant mothers to use, since it may cause harm to a developing fetus.
J was a prednisone rage 31-year-old woman with a five-year history of an overlap syndrome with features of systemic lupus erythematosus and systemic sclerosis. Two months prior to the current admission, she had been hospitalized with altered mental status. At that time, she underwent brain imaging, lumbar puncture, and cerebrospinal fluid analysis and was diagnosed with lupus cerebritis. She was treated with corticosteroids, and her mental status improved to baseline. Her steroid dose was tapered over four weeks without recurrence prednisone rage of altered mental status. J was then admitted to the general medicine service with acute renal failure that was attributed to lupus nephritis. She was started on intravenous methylprenisolone at a dose of 125 mg daily. Over the next three days, she was unable to sleep and developed rapid, pressured speech. Usually mild mannered and cooperative with the nursing staff, she became irritable and suspicious. Psychiatry consultation was requested for assistance in evaluating and managing her acute behavioral changes. J had no previous psychiatric history aside from her recent episode of lupus cerebritis and had not been treated with antipsychotic or antidepressant medications in the past. There was no family history of psychiatric illness or rheumatologic disorders. She was married and lived with her husband and 10-year-old son. She was currently experiencing financial difficulties related to her health problems. She denied any use of alcohol, cigarettes, or illicit drugs, and urine toxicology was negative. She had been following up with her rheumatologist and primary care provider and had been taking medications as prescribed. Because of the activity of the renal disease, Mrs. Js rheumatologic condition necessitated continued use of corticosteroids, although the dose of prednisone was tapered to 60 mg daily. At the same time, risperidone was added at a low dose and titrated up.5 mg in the morning and 2 mg at bedtime, with complete resolution of her manic symptoms. Over the next six months, she was able to be tapered off corticosteroids and risperidone without recurrence of the manic symptoms. The outcome of this case was fortunately favorable, with treatment decisions requiring extensive discussion between the general medicine service and the patients consultants, including the rheumatologist, psychiatrist, and nephrologist. As often occurs with lupus patients who develop psychiatric symptoms prednisone rage when treated with glucocorticoids, two major questions arise: Are the psychiatric symptoms from the steroids as opposed to the disease (e.g., cerebritis)? If they are from steroids, how can these symptoms best be treated? This article will provide a framework to decide the answers. Click for large version, background, corticosteroids are used to treat inflammatory manifestations of many rheumatologic conditions. Doses necessary to control disease are frequently high (e.g., 1 mg/kg or greater and therapy may be maintained for prolonged periods of weeks to months. In this setting, one out of every two to three patients prescribed steroids may develop psychiatric symptoms including psychosis, mania, delirium, and depression. The most common symptoms reported with corticosteroid therapy are hypomania, mania, and psychosis.1. Psychiatric Symptoms Associated with Corticosteroids, psychiatric symptoms have been documented in association with the use of corticosteroids since these agents were first introduced in the 1950s.2 Corticosteroid-induced psychosis refers to a spectrum of psychiatric symptoms ranging from subtle prednisone rage mood changes to memory deficits to frank. 40).3 Mania and hypomania are reported most commonly (35 followed by depressive symptoms (28) and psychotic reactions (24).2 Psychiatric symptoms typically develop three to four days after the initiation of corticosteroid therapy, although symptoms can occur at any time, including after cessation of therapy. We carry over 26,000 products and support you with easy ordering systems, fast delivery, and personal account management. We have the tools and the expertise to help you choose solutions that are right for your prednisone rage business goals. Were a local supplier supported by the countrys largest wholesale distributor. That transfers to big buying power and significant savings for you! Thats the assurance you need that your business will always have the products it needs to stay productive exactly when they are needed. We offer a unique Supply Cabinet Management service to manage your office supplies and eliminate down time in your office from depleted supplies.
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Generic Name: prednisone (pred ni sone brand Names: Rayos, Sterapred, medically reviewed on February 13, 2018. Prednisone is a corticosteroid. It prevents the release of substances in the body that cause inflammation. It also suppresses the immune system. Prednisone is used as prednisone 10mg used for an anti-inflammatory or an immunosuppressant medication. Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. You should not take prednisone if you have a fungal infection anywhere in your prednisone 10mg used for body. Steroid medication can weaken your immune system, making it easier for you to get an infection. Avoid being near people who are sick or have infections. Do not receive a "live" vaccine while using prednisone. Call your doctor at once if you have shortness of breath, severe pain in your upper stomach, bloody or tarry stools, severe depression, changes in personality or behavior, vision problems, or eye pain. You should not stop using prednisone suddenly. Follow your doctor's instructions about tapering your dose. Before taking this medicine, you should not use this medication if you are allergic to prednisone, or if you have a fungal infection anywhere in your body. Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks. To make sure prednisone is safe for you, tell your doctor if you have: any illness that causes diarrhea; liver disease (such as cirrhosis kidney disease; heart disease, high blood pressure, low levels of potassium in your blood; a thyroid disorder; diabetes; a history. Long-term use of steroids may lead to bone loss (osteoporosis especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk of osteoporosis. Prednisone can cause low birth weight or birth defects if you take the medicine during your first trimester. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Use effective birth control. Prednisone can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medicine. How should I take prednisone? Take prednisone exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take prednisone with food. Your dosage needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Do not change your medication dose or schedule without your doctor's advice. Measure liquid prednisone with a special dose-measuring spoon or medicine cup. If prednisone 10mg used for you do not have a dose-measuring device, ask your pharmacist for one. Do not crush, chew, or break a delayed-release tablet. While using prednisone, you may need frequent blood tests at your doctor's office. Your blood pressure may also need to be checked. This medication can cause unusual results with certain medical tests.